I think Skull Island would be the perfect DCC adventure spot. You could even have a series of adventures there. The characters obviously aren't filming a movie so I think the best way to get the party there is either promise of magic lore (perhaps a long dead archmage had a lair on the island) or the need to retrieve a cure or poison of some sort from a plant or animal only found on the island.
I was going to stat out the various creatures of the island, but a many already
have stats in the core book that work.
Skull Island Natives
Use Subhuman stats
Use Giant Ape-Man stats
Use Giant Lizard stats
Use Cave Cricket stats
Vile Meat Weasel
Use Colossal Leach stats
Use Man-Bat stats
The only thing really missing would be Vastatosaurus Rex stats. If any of the adventures or books have T-Rex stats, those would work just fine.
In addition the following creatures make sense to add to the island: Giant Ant, Bat, Giant Beetle, Cave Octopus, Giant Centipede, Insect Swarm, Killer Bee, Primeval Slime, Pterodactyl, Giant Rat, Giant Scorpion, Underdark Slug, Giant Snake, Vombis Leech.